Basic Pharmaceutical Chemistry

Subject Code : SFA-107

module description
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Module Name Basic Concepts of Therapy 
Module level, if applicable 2nd Year
Code, if applicable SFA-440
Semester (s) in which the module is taught Fourth Semester
Person responsible for the module Dr. Apt. Vitarani Dwi Ananda Ningrum, M.Si
Lecturer(s) Dr. Apt. Vitarani Dwi Ananda Ningrum, M.Si

apt. Yosi Febrianti, MSc.

apt. Ndaru Setyaningrum, MSc.
Language Bahasa Indonesia and English
Relation to curriculum Compulsory course 
Types of teaching and learning Class size Attendance time (hours per week per semester) Forms of active participation Workload
Lecture  50 3 Discussion  Lecture: 2 (hour) x 14 (meeting) 28
Preparation and follow up 4 (hour) x 14 (self-learning)

 

 56
Interprofessional Education (IPE)  50 Report Attendance time 1 (hour) x 12 (meeting)  12
Preparation and follow up 4 (hour) x 14 (self-learning) 24
Total workload 120 hours
ECTS 4.29 ECTS
Credit points 3 CU
Requirements according to examination regulations Minimum attendance at lectures is 75% (according to UII regulation). Final score is evaluated based on assignment and reports (40%), mid semester exam (30%), and end semester exam (30%).   
Recommended prerequisites Pharmacology
Related course –
Module objectives/intended learning By the end of this course students should be able to:

  1. Understand the role of pharmacist in different scopes of pharmaceutical work in science and technology as well as pharmaceutical care.
  2. Understand the role of pharmacists and that of other healthcare workers as part of a health professional team in healthcare facilities.
  3. Explain the definition, aims, medication-related issues, and impacts of irrational drug use, as well as the risk factors in patients with the high potential for irrational drug use.
  4. Explain the pharmacokinetic-pharmacodynamic changes of drugs in a specific population based on the physiological approach (pediatrics, geriatrics, pregnant women, breastfeeding mothers) and pathological approach (obesity-malnutrition, renal function disorders, liver function disorders) AND analyze their correlation with the principles of drug use.
  5. Explain the pharmacokinetic-pharmacodynamic changes of drugs in a specific population based on the physiological approach (pediatrics, geriatrics, pregnant women, breastfeeding mothers) AND analyze their correlation with the principles of drug use.
  6. Explain the pharmacokinetic-pharmacodynamic changes of drugs in a specific population based on the pathological approach (obesity-malnutrition, renal function disorders, liver function disorders) AND analyze their correlation with the principles of drug use.
  7. Describe the types of ADR and their examples and distinguish the types and mechanisms of drug interactions as well as the principles of ADR and drug interactions prevention and management AND correlate them with the risk factors for the occurrence of ADR and clinically relevant drug interactions.
  8. Describe the types of ADR and their examples as well as the principles of ADR prevention and management.
  9. Distinguish the SOAP method used by healthcare workers in integrated services for patients in healthcare facilities and classify data and information in a scenario of inpatients with a CHRONIC disease into S, O, A, and P parts from a pharmaceutical-care perspective AND use the SOAP method for patients with a disease in primary healthcare facilities.
  10. Apply the SOAP method in a case of patient with hypertension in primary healthcare facilities.
Content This course is designed for discussing the concept of drug therapy. It covers the theory and concepts on the role of pharmacists and other healthcare workers as part of a health professional team in healthcare facilities, rational therapy, the pharmacokinetic-pharmacodynamic changes of drugs in a specific population based on the physiological approach, ADR, and SOAP method
Study and examination requirements and forms of examination Mid-term, Final term, assignments and presentation
Media employed Textbooks, slides (power points), video, Google classroom
Reading lists

  1. Robert J. Cipolle, Linda M. Strand, Peter C. Morley, Pharmaceutical Care Practice: The Patient-Centered Approach to Medication Management Services, 3e, 2012, McGraw-Hill Medical

  2. Dipiro, JT., Talbert, RL., Yee., et al., 2017, Pharmacotherapy: Pathophysiologic approach, Pediatrics, 10th, Mc-Grawn-Hill
  3. Dipiro, JT., Talbert, RL., Yee., et al., 2017, Pharmacotherapy: Pathophysiologic approach, Geriatrics, 10th, Mc-Grawn-Hill
  4. Journal websites (www.nejm.org ; www.bmj.com journal ; www.cochrane.org; https://ebm.bmj.com/)
  5. Kemenkes RI (Indonesian Ministry of Health), 2011, Modul Penggunaan Obat Rasional (Rational Drug Use Module)
  6. WHO, 2002, Promoting rational use of medicines: core components
  7. Royal Pharmaceutical Society, 2016, Stockley’s Drug Interaction, Pharmaceutical Press
  8. Portofolio Pelayanan farmasi klinik PKPA Puskesmas PSPA UII (Portfolio of Clinical Pharmacy Services)
  9. http://perpustakaan.farmalkes.kemkes.go.id/uploaded_files/temporary/DigitalCollection/

ZjhmMWQ2OWNiYmZjOWFiYzA0NDdiZGJhNWYzMmNmZWUxMzZiMDMxYw==.pdf

  1. https://www.google.com/url?sa=i&url=http%3A%2F%2Ffarmalkes.kemkes.go.id%2Fv2%2F%3Fp%3D5387&psig=AOvVaw2nRvNuwryTFiTRtikt&ust=1580962952130000&source=images&cd

=vfe&ved=2ahUKEwjeqMuKyLnnAhWt4TgGHaXwAzwQr4kDegUIARDSAQ

  1. Al-Qur’an and Al-Hadith
Requirements according to examination regulations Minimum attendance at lectures is 75% (according to UII regulation). Final score is evaluated based on assignment and reports (50%) and exam (50%)  
Recommended prerequisites –
Related course –
Study and examination requirements and forms of examination Mid-term, Final term, presentation, quiz, assignment, and collaborative discussion

By the end of this course students should be able to:

  • play an active role and apply discipline in the lecture process.
  • explain the application of basic chemistry in pharmacy.
  • understand the concept of stoichiometry in the pharmaceutical field.
  • understand the concept of acid-base and reduction-oxidation reactions in the pharmaceutical field.
  • understand the concept of reaction kinetics and the colligative properties of solutions in the pharmaceutical field.

The course will cover: 

  • The physicochemical properties of medicinal compounds
  • Stoichiometry, acid-base reactions, reduction-oxidation reactions, kinetics reaction, and the colligative nature of solutions.

Text books, slides (power points), and video

  • Cairns, D., 2008, Essentials Pharmaceutical Chemistry 3rd edition, Pharmaceutical Press, London.
  • Harris, D. C., 2010, Quantitative Chemical Analysis Eighth Edition, W. H. Freeman and Company, New York.
  • Reddy I. K., dan Khan M. A., 2004, Essential Math and Calculation for Pharmacy technicians, CRC Press, Boca Raton, Florida.
  • Timberlake, K.C., 2015, Chemistry, An Introduction to General, Organic, and Biological Chemistry, 12th edition, Pearson Education Inc., USA.
  • Sarker S.D., dan Nahar L., 2007, Chemistry for Pharmacy Students, John Wiley & Sons, Ltd., England.
  • Beale J. M., Jr., dan Block J. H., 2011, Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry, twelfth edition, Lippincott Williams & Wilkins, Philadelphia