SFA-107: Organic Chemistry

1. Course Identification
Course Organic Chemistry
Faculty Mathematics and Natural Sciences Study Program Pharmacy
Code SFA-106 Credits 3 credits
Group Study Program Status Compulsory
Semester I (First) Availability Limited in Study Program
Learning Method Class Media online
Cluster Biomedical and Pharmaceutical Sciences: Pharmaceutical Chemistry Prerequisite
2. Course Description

Mata kuliah Kimia Organik dalam Kurikulum Farmasi 2017 diberikan kepada mahasiswa semester I (satu) dengan bobot 3 sks. Mata kuliah ini merupakan mata kuliah wajib yang dapat ditempuh tanpa prasyarat.  Mata Kuliah ini bertujuan untuk mendukung Capaian Pembelajaran Lulusan berupa kemampuan untuk berperilaku profesional dan etis serta pengetahuan dasar ilmu kefarmasian. Pada mata kuliah ini mahasiswa akan mempelajari tentang Struktur dan hibridisasi atom, jenis ikatan, jenis interaksi antar senyawa, stereokimia, asam basa berdasar struktur, sifat fisikokimia senyawa berdasarkan gugus fungsinya, struktur, sifat kimia dan geometri senyawa makromolekul, reaksi substitusi dan tautomeri keto-enol. Mahasiswa juga dibiasakan untuk bersikap jujur serta disiplin selama mengikuti perkuliahan ini.

1. Learning Outcome
LO Code LO
SIF3 Able to carefully and thoroughly apply responsible attitude, dedication and punctuality based on sincerity, honesty and integrity at work along with the ability to show bravery in expressing the truth whilst maintaining politeness, ethics and affection and promoting mutual benefit.
PEF1 Able to comprehend the theories, methods and concepts within the scope of pharmaceutical sciences and technologies in the disciplines of pharmaceutics, pharmacognosy, pharmaceutical chemistry and pharmacology as well as their application in pharmaceutical works.
2. Course Learning Outcome and indicators
Supported LO Code CLO Code CLO and indicators
SIF3 CLO1 Students have an attitude of responsibility, dedication, honesty and discipline in attending lectures and doing assignments or quizzes synchronously or asynchronously.

1.    Students attend synchronous meetings and collect assignments according to a set schedule

2.    Students take asynchronous lectures in a disciplined manner and carry out any accompanying activities completely and according to the time allocation provided.

PEF1 CLO2 Students are able to explain atomic structure, bonds and isomerism; Acid-base; Hydrocarbons; Aromatic compounds; Stereoisomer; Alkyl halides and substitution-elimination reactions; Alcohol, phenol and thiol; Ether and epoxide

1.     Students are able to correctly explain atomic structure, bonds and isomerism; Acid-base; Hydrocarbons; Aromatic compounds; Stereoisomer; Alkyl halides and substitution-elimination reactions; Alcohol, phenol and thiol; Ether and epoxide

CLO3 Students are able to explain aldehyde and ketones; Carboxylate compounds and their derivatives; Carbohydrate; Lipids and soaps; Amino acids, peptides and proteins; Nucleotides and nucleic acids

1.     Students are able to correctly explain aldehyde and ketones; Carboxylate compounds and their derivatives; Carbohydrate; Lipids and soaps; Amino acids, peptides and proteins; Nucleotides and nucleic acids

CLO4 Students are able to analyze physicochemical properties based on functional groups and apply organic chemistry theory in pharmaceutical practice

1.     Students are able to correctly analyze physicochemical properties based on functional groups and correctly apply organic chemistry theory in pharmaceutical practice

3. Course Learning Outcome Map Analysis

Primary References

  1. Hart DJ, Hadad CM, Craine LE, Hart H. 2012. Organic Chemistry: A Short Course 13th Ed., Brooks/Cole CENGAGE Learning, USA
  2. Winter A. 2008. Organic Chemistry I Workbook for Dummies. Wiley Publishing Inc. Canada
  3. Dewick PM. 2006. Essentials of Organic Chemistry for students of pharmacy, medicinal chemistry and biological chemistry. John Wiley and Sons Ltd. England
1. Learning activities
Sesion CLO Topic Learning activities
1 CLO2 Introduction Introduction from lecturer:

1.     Learning contracts

2.     Learning activities

3.     Introduction of Marvin Sketch

4.     Introduction of Organic Chemistry

5.     Case discussion: importances of organic chemistry in Pharmacy

2 CLO2 Atomic structure, bonds and isomerism The lecturer explains about

1.     How electrons are arranged in atoms

2.     Ionic and covalent bonding

3.     Valence

4.     Isomerism

5.     Structural fomulas

6.     Classification according to functional groups

Students independently practice working on problems

3 CLO2 Hydrocarbons The lecturer explains about

•      Alkanes and Cycloalkanes

•      Alkenes and Alkynes

Students independently practice working on problems

4 CLO2 Aromatic compounds Students study videos and slides (50 minutes)

Students do assignments (100 minutes)

5 CLO2 Stereoisomer The lecturer explains about

•      Chirality and enantiomers

•      Configuration and the R-S convention

•      Stereochemistry

Case: Thalidomide

Students independently practice working on problems

6 CLO2 Alcohol, phenol and thiol; Ether and epoxide Students study videos and slides (50 minutes)

Students do assignments (100 minutes)

7 CLO2 Alkyl halides and substitution-elimination reactions The lecturer explains about

•      Alkyl halides

•      Nucleophilic substitution

•      Elimination reaction

Case: halogenated organic compounds from the sea

Students independently practice working on problems

8 CLO2 Midterm exam Students do written questions (100 minutes).
9 CLO1

CLO3

CLO4

Aldehyde & Keton The lecturer explains about aldehydes and ketones

• Nomenclature

• The carbonyl groups

• Keto-enol tautomerism

• The acidity of α-hydrogens

Students discuss the case given

Case1: Aldehyde/ketone compounds in nature

Students independently practice working on problems

10 CLO4 Application of organic chemistry in pharmaceutical practices Students study slides (30 minutes)

Students work on cases through group discussions and upload discussion results through classroom (120 minutes)

11 CLO3 Carboxylic Acids and Their Derivatives The lecturer explains about carboxylic acids and their derivatives

• Carboxylic acid nomenclature

• Characteristics, acidity and α-hydrogen

• Carboxylate derivatives and nomenclature

• Reaction to salt formation and saponification

Students discuss the case given

Case2: Green chemistry in the synthesis of carboxylic acids

Students independently practice working on problems

12 CLO1

CLO3

Carbohydrate The lecturer explains about carbohydrates

• Definition and classification

• Cyrillic monosaccharides

• Cyclic hemiacetal structure

• Pyranose and furanose

• Formation of glycoside bonds

Students discuss the case given

Case3: Artificial fat from carbohydrates

Students independently practice working on problems

13 CLO3

CLO4

Lipids and Detergents Students study videos and slides (50 minutes)

Students do assignments (100 minutes)

14 CLO1

CLO3

Amino acid, peptide and protein The lecturer explains about amino acids, peptides and proteins

Students independently practice working on problems

15 CLO1

CLO3

Nucleotide and nucleic acids The lecturer explains about nucleotides and nucleic acids

Students independently practice working on problems

16 CLO3 Final exam Students do written questions (100 minutes).
2. Learning Experience
CLO Code Learning Process
CLO1 Synchronous and asynchronous online learning. Self-study using the Marvin Sketch and Google Form programs
CLO2 Synchronous and asynchronous online learning. Self-study using the Marvin Sketch and Google Form programs
CLO3 Synchronous and asynchronous online learning. Self-study using the Marvin Sketch and Google Form programs
CLO4 Synchronous and asynchronous online learning. Group discussion to solve cases
1. Assessment
CLO Code Assessment Weight
CLO1 Presence and liveliness on time submission of assignments

Independent learning activities

10%
CLO2 Assignment

Quiz

Examination

40%
CLO3 Assignment

Quiz

Examination

35%
CLO4 Assignments. 15%
2. Grading and Evaluation Systems

Grading system uses reference assessment as follows:

Letter Value Weight Minimum Value Value Range
A 4 80 80.00 – 100
A- 3.75 77.5 77.50 – 79.99
A/B 3.5 75 75.00 – 77.49
B+ 3.25 72.5 72.50 – 74.99
B 3 70 70.00 – 72.49
B- 2.75 67.5 67.50 – 69.99
B/C 2.5 65 65.00 – 67.49
C+ 2.25 62.5 62.50 – 64.99
C 2 60 60.00 – 62.49
C- 1.75 55 55.00 – 59.99
C/D 1.5 50 50.00 – 54.99
D+ 1.25 45 45.00 – 49.99
D 1 40 40.00 – 44.99
E 0 0 < 40

Evaluation Systems

Students must achieve a grade of at least 40 for average total course learning outcome. If it does not meet the requirements, they must carry out the test/remedial.