COURSE INFORMATION
| Module Name | Drug Design | ||||
| Module level, if applicable | 4th year | ||||
| Code, if applicable | SFA-990 | ||||
| Semester (s) in which the module is taught | Seventh semester | ||||
| Person responsible for the module | apt. Pinus Jumaryatno, M. Phill, Ph.D | ||||
| Lecturer(s) | apt. Pinus Jumaryatno, M. Phill, Ph.DDra. apt. Suparmi, M.Si. | ||||
| Language | English- Indonesia | ||||
| Relation to curriculum | Elective course | ||||
REQUIREMENTS
| Requirements according to examination regulations | Minimum attendance at lectures is 75% (according to UII regulation). |
| Recommended prerequisites | – |
| Related course | – |
| Study and examination requirements and forms of examination | Midterm and final term, project assignment and presentation |
MODULE OBJECTIVES/INTENDED LEARNING
By the end of this course students should be able to:
- properly explain the basics of rational drug development
- describe the physicochemical properties that affect drug action, drug-receptor binding and interactions, the basis of drug-receptor binding
- explain the basic principles in QSAR which include physicochemical properties and iso/bioisotsterism
- explain the basic principles of prodrug, the purpose of its formation, as well as prodrug design and activation mechanism
- describe the basic principles of structure based design, especially for enzyme as target; rational enzyme inhibitor design
- outlines the principles of receptor based design and their applications
- apply computer aided drugs design for molecular modeling
- properly describe and explain the basic concepts of combinatorial chemistry and their applications
CONTENT
1. Rational drug development and physicochemical properties influencing drug action
2. Drug-receptor interactions
3. QSAR
4. Prodrug
5. Structure based design
6. Computer aided drug design
7. Combinatorial chemistry
MEDIA EMPLOYED
Blended Learning
READING LISTS
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